منابع مشابه
ClpX eats randomly
JCB • VOLUME 171 • NUMBER 3 • 2005 406 Divided identities in the niche o maintain a stem cell niche at a fixed size, the niche exerts control over both cell differentiation (how many cells functionally leave the niche) and cell division. G. Venugopala Reddy and Elliot Meyerowitz (Caltech, Pasadena, CA) now show that, in the growing shoots of plants, these two control points are separable in bot...
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If one believes that vegetarianism is morally obligatory, there are numerous ways to argue for that conclusion. In this paper, classic utilitarian and rights-based attempts to ground this obligation are considered, as well as Cora Diamond’s reframing of the debate in terms of the proper way to view other animals. After discussion of these three ways to ground the obligation and their problems, ...
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Self-mutilation is a general term for a variety of forms of intentional self-harm without the wish to die. Although there have been many reports of self-mutilation injuries in the literature, none have reported self-cannibalism after self-mutilation. In this article we present a patient with self-cannibalism following self-mutilation. A 34-year-old male patient was brought to the emergency depa...
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Autophagy is a cellular process by which cellular components are engulfed inside distinct double-membrane structures (autophagosomes) and shuttled to the lysosomes for degradation. In addition to non-selective, bulk degradation of cytoplasmic contents, autophagosomes can selectively recycle unwanted organelles, remove protein aggregates, and eliminate invading viruses [1-4]. In recent years, th...
متن کاملClpX interactions with ClpP, SspB, protein
The ssrA-degradation tag sequence contains contiguous binding sites for the SspB adaptor and the ClpX component of the ClpXP protease. Although SspB normally enhances ClpXP degradation of ssrA-tagged substrates, it inhibits proteolysis under conditions that prevent tethering to ClpX. By increasing the spacing between the protease and adaptor binding determinants in the ssrA tag, substrates were...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2005
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb1713rr1